Requirements
- Target platform
- OpenClaw
- Install method
- Manual import
- Extraction
- Extract archive
- Prerequisites
- OpenClaw
- Primary doc
- SKILL.md
Tencent SkillHub Β· AI
Clarity Submit
Submit a protein variant hypothesis to Clarity Protocol for validation and folding. Use when the user asks to submit a hypothesis, propose a protein variant,...
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Submit a protein variant hypothesis to Clarity Protocol for validation and folding. Use when the user asks to submit a hypothesis, propose a protein variant,...
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Quick setup
- Download the package from Yavira.
- Extract the archive and review SKILL.md first.
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Package facts
- Download mode
- Yavira redirect
- Package format
- ZIP package
- Source platform
- Tencent SkillHub
- What's included
- SKILL.md, scripts/api_client.py, scripts/check_status.py, scripts/submit_hypothesis.py
Validation
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Trust & source
Release facts
- Source
- Tencent SkillHub
- Verification
- Indexed source record
- Version
- 1.0.0
Provenance
- Publisher
- clarityprotocol
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Documentation
Clarity Submit Skill
Submit protein variant hypotheses to Clarity Protocol for automated validation and ColabFold structural prediction.
Quick Start
Submit a hypothesis: python scripts/submit_hypothesis.py --protein SOD1 --variant A4V --rationale "ALS-linked mutation with unknown structural impact" Submit with optional fields: python scripts/submit_hypothesis.py --protein MAPT --variant P301L --rationale "Tau pathology in frontotemporal dementia" --wallet "YOUR_SOLANA_WALLET" Check hypothesis status: python scripts/check_status.py --id 42
Setup
Set your write API key: export CLARITY_WRITE_KEY=your_write_key_here Contact the Clarity Protocol team to request a write API key.
What Happens After Submission
Feasibility validation runs automatically against UniProt, ClinVar, gnomAD, and PubMed If validated, the hypothesis is auto-queued for ColabFold structural prediction Four AI research agents continuously monitor the variant for new findings Results are available at the tracking URL returned after submission
Request Fields
--protein (required): Protein name (e.g., SOD1, MAPT, APP, SNCA) --variant (required): Variant notation (e.g., A4V, P301L, G2019S) --rationale (required): Why this variant is worth investigating (min 10 characters) --disease (optional): Disease area (auto-detected from protein if omitted) --wallet (optional): Solana wallet address for $FOLD reward eligibility
Response Fields
id: Unique hypothesis identifier protein_name: Normalized protein name variant_notation: Variant as submitted status: Current status (submitted, validating, validated, queued, folding, complete, rejected) tracking_url: URL to track progress on clarityprotocol.io
Rate Limits
Write (POST): 10 submissions per day per key Read (GET): 100 requests per minute per key
Size Limits
Proteins up to 1,500 residues can be folded. Larger proteins (e.g., LRRK2 at 2,527 residues) exceed hardware capacity and will be rejected during validation.
Error Handling
403 Forbidden: Invalid or missing write API key. Set CLARITY_WRITE_KEY env var. 422 Validation Error: Invalid input (protein name empty, rationale too short, etc.). 429 Rate Limit: You've exceeded 10 submissions/day. Wait until tomorrow.
Use Cases
Programmatically submit variants for investigation Integrate Clarity Protocol into research pipelines Batch submission of variants of interest Agent-driven hypothesis generation and submission
Category context
Agent frameworks, memory systems, reasoning layers, and model-native orchestration.
Source: Tencent SkillHub
Largest current source with strong distribution and engagement signals.
Package contents
Included in package
3 Scripts1 Docs
- SKILL.md
- scripts/api_client.py
- scripts/check_status.py
- scripts/submit_hypothesis.py