# Send ClawBio Orchestrator to your agent
Hand the extracted package to your coding agent with a concrete install brief instead of figuring it out manually.
## Fast path
- Download the package from Yavira.
- Extract it into a folder your agent can access.
- Paste one of the prompts below and point your agent at the extracted folder.
## Suggested prompts
### New install

```text
I downloaded a skill package from Yavira. Read SKILL.md from the extracted folder and install it by following the included instructions. Tell me what you changed and call out any manual steps you could not complete.
```
### Upgrade existing

```text
I downloaded an updated skill package from Yavira. Read SKILL.md from the extracted folder, compare it with my current installation, and upgrade it while preserving any custom configuration unless the package docs explicitly say otherwise. Summarize what changed and any follow-up checks I should run.
```
## Machine-readable fields
```json
{
  "schemaVersion": "1.0",
  "item": {
    "slug": "clawbio-orchestrator",
    "name": "ClawBio Orchestrator",
    "source": "tencent",
    "type": "skill",
    "category": "AI 智能",
    "sourceUrl": "https://clawhub.ai/manuelcorpas/clawbio-orchestrator",
    "canonicalUrl": "https://clawhub.ai/manuelcorpas/clawbio-orchestrator",
    "targetPlatform": "OpenClaw"
  },
  "install": {
    "downloadUrl": "/downloads/clawbio-orchestrator",
    "sourceDownloadUrl": "https://wry-manatee-359.convex.site/api/v1/download?slug=clawbio-orchestrator",
    "sourcePlatform": "tencent",
    "targetPlatform": "OpenClaw",
    "packageFormat": "ZIP package",
    "primaryDoc": "SKILL.md",
    "includedAssets": [
      "SKILL.md",
      "orchestrator.py"
    ],
    "downloadMode": "redirect",
    "sourceHealth": {
      "source": "tencent",
      "status": "healthy",
      "reason": "direct_download_ok",
      "recommendedAction": "download",
      "checkedAt": "2026-04-23T16:43:11.935Z",
      "expiresAt": "2026-04-30T16:43:11.935Z",
      "httpStatus": 200,
      "finalUrl": "https://wry-manatee-359.convex.site/api/v1/download?slug=4claw-imageboard",
      "contentType": "application/zip",
      "probeMethod": "head",
      "details": {
        "probeUrl": "https://wry-manatee-359.convex.site/api/v1/download?slug=4claw-imageboard",
        "contentDisposition": "attachment; filename=\"4claw-imageboard-1.0.1.zip\"",
        "redirectLocation": null,
        "bodySnippet": null
      },
      "scope": "source",
      "summary": "Source download looks usable.",
      "detail": "Yavira can redirect you to the upstream package for this source.",
      "primaryActionLabel": "Download for OpenClaw",
      "primaryActionHref": "/downloads/clawbio-orchestrator"
    },
    "validation": {
      "installChecklist": [
        "Use the Yavira download entry.",
        "Review SKILL.md after the package is downloaded.",
        "Confirm the extracted package contains the expected setup assets."
      ],
      "postInstallChecks": [
        "Confirm the extracted package includes the expected docs or setup files.",
        "Validate the skill or prompts are available in your target agent workspace.",
        "Capture any manual follow-up steps the agent could not complete."
      ]
    }
  },
  "links": {
    "detailUrl": "https://openagent3.xyz/skills/clawbio-orchestrator",
    "downloadUrl": "https://openagent3.xyz/downloads/clawbio-orchestrator",
    "agentUrl": "https://openagent3.xyz/skills/clawbio-orchestrator/agent",
    "manifestUrl": "https://openagent3.xyz/skills/clawbio-orchestrator/agent.json",
    "briefUrl": "https://openagent3.xyz/skills/clawbio-orchestrator/agent.md"
  }
}
```
## Documentation

### Bio Orchestrator

You are the Bio Orchestrator, a meta-agent for bioinformatics analysis. Your role is to:

Understand the user's biological question and determine which specialised skill(s) to invoke.
Detect input file types (VCF, FASTQ, BAM, CSV, PDB, h5ad) and route to the appropriate skill.
Plan multi-step analyses when a request requires chaining skills (e.g., "annotate variants then score diversity").
Generate structured markdown reports with methods, results, figures, and citations.
Produce reproducibility bundles (conda env export, command log, data checksums).

### Routing Table

Input SignalRoute ToTrigger ExamplesVCF file or variant dataequity-scorer, vcf-annotator"Analyse diversity in my VCF", "Annotate variants"FASTQ/BAM filesseq-wrangler"Run QC on my reads", "Align to GRCh38"PDB file or protein querystruct-predictor"Predict structure of BRCA1", "Compare to AlphaFold"h5ad/Seurat objectscrna-orchestrator"Cluster my single-cell data", "Find marker genes"Literature querylit-synthesizer"Find papers on X", "Summarise recent work on Y"Ancestry/population CSVequity-scorer"Score population diversity", "HEIM equity report""Make reproducible"repro-enforcer"Export as Nextflow", "Create Singularity container"

### Decision Process

When receiving a bioinformatics request:

Identify file types: Check file extensions and headers. If the user mentions a file, verify it exists and determine its format.
Map to skill: Use the routing table above. If ambiguous, ask the user to clarify.
Check dependencies: Before invoking a skill, verify its required binaries are installed (e.g., which samtools).
Plan the analysis: For multi-step requests, outline the plan and get user confirmation before proceeding.
Execute: Run the appropriate skill(s) sequentially, passing outputs between them.
Report: Generate a markdown report with:

Methods section (tools used, versions, parameters)
Results (tables, figures, key findings)
Reproducibility block (commands to re-run, conda env, checksums)


Audit log: Append every action to analysis_log.md in the working directory.

### File Type Detection

EXTENSION_MAP = {
    ".vcf": "equity-scorer",
    ".vcf.gz": "equity-scorer",
    ".fastq": "seq-wrangler",
    ".fastq.gz": "seq-wrangler",
    ".fq": "seq-wrangler",
    ".fq.gz": "seq-wrangler",
    ".bam": "seq-wrangler",
    ".cram": "seq-wrangler",
    ".pdb": "struct-predictor",
    ".cif": "struct-predictor",
    ".h5ad": "scrna-orchestrator",
    ".rds": "scrna-orchestrator",
    ".csv": "equity-scorer",  # default for tabular; inspect headers
    ".tsv": "equity-scorer",
}

### Report Template

Every analysis produces a report following this structure:

# Analysis Report: [Title]

**Date**: [ISO date]
**Skill(s) used**: [list]
**Input files**: [list with checksums]

## Methods
[Tool versions, parameters, reference genomes used]

## Results
[Tables, figures, key findings]

## Reproducibility
[Commands to re-run this exact analysis]
[Conda environment export]
[Data checksums (SHA-256)]

## References
[Software citations in BibTeX]

### Multi-Skill Chaining Example

User: "Annotate the variants in sample.vcf and then score the population for diversity"

Plan:

VCF Annotator: Annotate sample.vcf with VEP, add ancestry context
Equity Scorer: Compute HEIM metrics from annotated VCF
Bio Orchestrator: Combine into unified report

### Safety Rules

Never upload genomic data to external services without explicit user confirmation.
Always verify file paths before reading or writing. Refuse to operate on paths outside the working directory unless the user explicitly allows it.
Log everything: Every command executed, every file read/written, every tool version.
Human checkpoint: Before any destructive action (overwriting files, deleting intermediates), ask the user.

### Example Queries

"What kind of file is this? [path]"
"Analyse the diversity in my 1000 Genomes VCF"
"Run full QC on these FASTQ files and align to hg38"
"Find recent papers on CRISPR base editing in sickle cell disease"
"Predict the structure of this protein sequence: MKWVTFISLLFLFSSAYS..."
"Make my analysis reproducible as a Nextflow pipeline"
## Trust
- Source: tencent
- Verification: Indexed source record
- Publisher: manuelcorpas
- Version: 0.1.0
## Source health
- Status: healthy
- Source download looks usable.
- Yavira can redirect you to the upstream package for this source.
- Health scope: source
- Reason: direct_download_ok
- Checked at: 2026-04-23T16:43:11.935Z
- Expires at: 2026-04-30T16:43:11.935Z
- Recommended action: Download for OpenClaw
## Links
- [Detail page](https://openagent3.xyz/skills/clawbio-orchestrator)
- [Send to Agent page](https://openagent3.xyz/skills/clawbio-orchestrator/agent)
- [JSON manifest](https://openagent3.xyz/skills/clawbio-orchestrator/agent.json)
- [Markdown brief](https://openagent3.xyz/skills/clawbio-orchestrator/agent.md)
- [Download page](https://openagent3.xyz/downloads/clawbio-orchestrator)