Requirements
- Target platform
- OpenClaw
- Install method
- Manual import
- Extraction
- Extract archive
- Prerequisites
- OpenClaw
- Primary doc
- SKILL.md
Analyze biological data using Lobster AI — single-cell RNA-seq, bulk RNA-seq, literature mining, dataset discovery, quality control, and visualization. USE THIS SKILL WHEN: - Analyzing single-cell or bulk RNA-seq data - Searching PubMed/GEO for papers or datasets - Running quality control on biological data - Clustering cells, finding markers, differential expression - Creating publication-quality visualizations - Working with H5AD, CSV, 10X, GEO/SRA accessions TRIGGER PHRASES: "analyze cells", "search PubMed", "download GEO", "run QC", "cluster", "find markers", "differential expression", "UMAP", "volcano plot", "single-cell", "RNA-seq", "bioinformatics" ASSUMES: Lobster is installed and configured. For setup issues, tell user to run `lobster config-test` and fix any errors before proceeding.
Analyze biological data using Lobster AI — single-cell RNA-seq, bulk RNA-seq, literature mining, dataset discovery, quality control, and visualization. USE THIS SKILL WHEN: - Analyzing single-cell or bulk RNA-seq data - Searching PubMed/GEO for papers or datasets - Running quality control on biological data - Clustering cells, finding markers, differential expression - Creating publication-quality visualizations - Working with H5AD, CSV, 10X, GEO/SRA accessions TRIGGER PHRASES: "analyze cells", "search PubMed", "download GEO", "run QC", "cluster", "find markers", "differential expression", "UMAP", "volcano plot", "single-cell", "RNA-seq", "bioinformatics" ASSUMES: Lobster is installed and configured. For setup issues, tell user to run `lobster config-test` and fix any errors before proceeding.
Hand the extracted package to your coding agent with a concrete install brief instead of figuring it out manually.
I downloaded a skill package from Yavira. Read SKILL.md from the extracted folder and install it by following the included instructions. Tell me what you changed and call out any manual steps you could not complete.
I downloaded an updated skill package from Yavira. Read SKILL.md from the extracted folder, compare it with my current installation, and upgrade it while preserving any custom configuration unless the package docs explicitly say otherwise. Summarize what changed and any follow-up checks I should run.
Lobster AI is a multi-agent bioinformatics platform. You interact via natural language or slash commands — Lobster routes to specialist agents automatically.
If Lobster is not installed, guide the user to the right command for their platform:
curl -fsSL https://install.lobsterbio.com | bash
irm https://install.lobsterbio.com/windows | iex
uv tool install 'lobster-ai[full,anthropic]' && lobster init # or: pip install 'lobster-ai[full]' && lobster init After install, lobster init configures API keys and selects agent packages.
uv tool: uv tool upgrade lobster-ai pip: pip install --upgrade lobster-ai
Users with uv tool installs add agents via: uv tool install lobster-ai --with lobster-transcriptomics --with lobster-proteomics Running lobster init will guide this process and generate the command.
TaskReferenceCLI commandsreferences/cli-commands.mdSingle-cell analysisreferences/single-cell-workflow.mdBulk RNA-seq analysisreferences/bulk-rnaseq-workflow.mdLiterature & datasetsreferences/research-workflow.mdVisualizationreferences/visualization.mdAvailable agentsreferences/agents.md
lobster chat # Start interactive session lobster chat --workspace ./myproject # Custom workspace lobster chat --reasoning # Enable detailed reasoning
lobster query "Your request" lobster query --session-id latest "Follow-up request"
Just describe what you want: "Download GSE109564 and run quality control" "Cluster the cells and find marker genes" "Compare hepatocytes vs stellate cells"
/data # Show loaded data info /files # List workspace files /workspace list # List available datasets /workspace load 1 # Load dataset by index /plots # Show generated visualizations /save # Save current session /status # Show system status /help # All commands
# Start named session lobster query --session-id "my_analysis" "Load GSE109564" # Continue with context lobster query --session-id latest "Now cluster the cells" lobster query --session-id latest "Find markers for cluster 3"
Lobster routes to specialist agents automatically: AgentHandlesSupervisorRoutes queries, coordinates agentsResearch AgentPubMed search, GEO discovery, paper extractionData ExpertFile loading, format conversion, downloadsTranscriptomics ExpertscRNA-seq: QC, clustering, markersDE Analysis ExpertDifferential expression, statistical testingAnnotation ExpertCell type annotation, gene set enrichmentVisualization ExpertUMAP, heatmaps, volcano plotsProteomics ExpertMass spec analysis [alpha]Genomics ExpertVCF, GWAS, variant analysis [alpha]ML ExpertEmbeddings, classification [alpha]
Default workspace: .lobster_workspace/ Output files: ExtensionContent.h5adProcessed AnnData objects.htmlInteractive visualizations.pngPublication-ready plots.csvExported tables.jsonMetadata, provenance Managing outputs: /files # List all outputs /plots # View visualizations /open results.html # Open in browser /read summary.csv # Preview file contents
# 1. Start session lobster chat --workspace ./my_analysis # 2. Load or download data "Download GSE109564 from GEO" # or /workspace load my_data.h5ad # 3. Quality control "Run quality control and show me the metrics" # 4. Analysis "Filter low-quality cells, normalize, and cluster" # 5. Interpretation "Identify cell types and find marker genes" # 6. Visualization "Create UMAP colored by cell type" /plots # 7. Export "Export marker genes to CSV" /save
IssueCheckLobster not respondinglobster config-testNo data loaded/data to verify, /workspace list to see availableAnalysis failsTry with --reasoning flagMissing outputsCheck /files and workspace directory
Online docs: docs.omics-os.com Key sections: Guides → CLI Commands Guides → Data Analysis Workflows Tutorials → Single-Cell RNA-seq Agents → Package documentation
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