Requirements
- Target platform
- OpenClaw
- Install method
- Manual import
- Extraction
- Extract archive
- Prerequisites
- OpenClaw
- Primary doc
- SKILL.md
Search and evaluate biomedical literature with effective queries, filters, and critical appraisal.
Search and evaluate biomedical literature with effective queries, filters, and critical appraisal.
Hand the extracted package to your coding agent with a concrete install brief instead of figuring it out manually.
I downloaded a skill package from Yavira. Read SKILL.md from the extracted folder and install it by following the included instructions. Tell me what you changed and call out any manual steps you could not complete.
I downloaded an updated skill package from Yavira. Read SKILL.md from the extracted folder, compare it with my current installation, and upgrade it while preserving any custom configuration unless the package docs explicitly say otherwise. Summarize what changed and any follow-up checks I should run.
Use MeSH terms for precise searching โ controlled vocabulary ensures you find related concepts regardless of wording Boolean operators must be uppercase: AND, OR, NOT โ lowercase is ignored Phrase searching with quotes: "heart failure" not heart failure โ unquoted searches terms separately Field tags narrow searches: [Title], [Author], [MeSH Terms] โ example: aspirin[Title] AND prevention[MeSH] Truncation with asterisk: therap* finds therapy, therapies, therapeutic
Article type matters: Clinical Trial, Systematic Review, Meta-Analysis โ filter by study design Publication date for recent evidence โ older studies may be superseded Free full text filter if access is limited โ but don't ignore paywalled high-quality studies Humans filter excludes animal studies โ relevant for clinical questions Language filter if translation isn't feasible
Systematic reviews and meta-analyses synthesize multiple studies โ start here for established topics Randomized controlled trials (RCTs) are gold standard for interventions โ but not all questions are answerable by RCT Cohort studies for long-term outcomes and rare exposures Case-control for rare diseases Case reports are lowest evidence โ interesting but not generalizable Guidelines synthesize evidence into recommendations โ check who wrote them and when
Sample size matters โ small studies may show effects that don't replicate Check confidence intervals, not just p-values โ narrow CI with meaningful effect size beats p<0.05 Funding source and conflicts of interest affect interpretation โ industry-funded studies favor sponsors Primary vs secondary outcomes โ cherry-picking significant secondary outcomes is common Intention-to-treat vs per-protocol analysis โ ITT is more conservative and realistic
Abstract conclusions may oversell results โ read methods and results sections Single studies rarely settle questions โ look for replication and systematic reviews Statistical significance isn't clinical significance โ 1% improvement may not matter to patients Retracted papers still appear in searches โ check Retraction Watch for controversial papers Predatory journals publish low-quality research โ verify journal reputation Preprints haven't been peer-reviewed โ useful for speed but not vetted
PICO framework: Patient/Population, Intervention, Comparison, Outcome โ structures clinical questions Start broad, then narrow with filters โ missing relevant papers worse than sorting through extras Save searches for ongoing monitoring โ PubMed can email when new papers match Related Articles feature finds similar papers โ useful after finding one good paper Citation tracking: who cited this paper? โ follow research forward in time
Impact factor indicates journal prestige, not individual paper quality First and last authors typically did the work and led the project Corresponding author handles questions โ contact for clarifications Check author affiliations โ institutional reputation matters Methods section determines if results are trustworthy โ results are only as good as methods
Treatment efficacy: RCTs and systematic reviews first Diagnosis accuracy: sensitivity/specificity studies Prognosis: cohort studies with long follow-up Etiology/harm: cohort or case-control studies Prevention: RCTs when available, cohort otherwise
PubMed is free but full text often isn't โ check institutional access, Unpaywall, or request from authors PMID is the unique identifier โ use it for precise citations Export to reference manager (EndNote, Zotero) โ manual citation is error-prone Clinical Queries filter pre-filters for clinical relevance โ therapy, diagnosis, prognosis, etiology Similar Articles and Cited By expand discovery โ algorithm finds related work
No control group for intervention studies Conclusions not supported by data presented Missing or inadequate statistical analysis Selective reporting of outcomes Conflicts of interest not disclosed Extraordinary claims without extraordinary evidence
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